Overview
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.2
USERS' SCORE
Good
Based on 10 Reviews
8.4
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
1,360 mcg DFE** (800 mcg folic acid)
340%
Vitamin B-12 (as Cyanocobalamin)
25 mcg
1042%
Top Medical Research Studies
9
We conducted a study with 70 menopausal women, randomly assigning them to receive either folic acid or a placebo for four weeks. Through questionnaires and hot flash diaries, we monitored changes in the severity, duration, and frequency of hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
3
We conducted a double-blind, placebo-controlled trial involving 164 postmenopausal women suffering from frequent hot flashes. Over 12 weeks, half received a daily 5 mg folic acid supplement, while the other half received a placebo.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
8
We investigated the effects of folic acid on hot flashes in postmenopausal women. In our study, 46 women were divided into two groups: one received daily folic acid supplements, while the other received a placebo for four weeks.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Most Useful Reviews
9
Eases hot flashes
2 people found this helpful
Really works. It is very helpful for easing hot flashes of menopause and assists thyroid function. I previously used it for period pain, taking two pills at the onset, and within ten minutes the pain would diminish. If I didn't achieve complete relief, I would repeat the dose and, like magic, no more cramps. It also boosts energy for those with ME/CFS or constant tiredness. I appreciate that it contains B12 as well. A definite thumbs up from me. :)
9
Eases hot flashes
Indispensable during menopause. I have early menopause, and my gynecologist recommended folic acid, magnesium, calcium, and vitamin D. Headaches have ceased, sleep is normal, and mood swings have smoothed. My hot flashes occur much less often now. I am satisfied with this manufacturer's folic acid. I hope my review is helpful.
9
Eases hot flashes
This gives me energy and alleviates hot flashes at the beginning of menopause and PMS. My nervous system feels calmer, and I am less irritable. I can see the results, which makes me pleased.
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.2
- All Researches
9
We conducted a study with 70 menopausal women, randomly assigning them to receive either folic acid or a placebo for four weeks. Through questionnaires and hot flash diaries, we monitored changes in the severity, duration, and frequency of hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
8
We investigated the effects of folic acid on hot flashes in postmenopausal women. In our study, 46 women were divided into two groups: one received daily folic acid supplements, while the other received a placebo for four weeks.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
7
We explored whether folic acid supplementation could help alleviate hot flashes in postmenopausal women. The study highlighted that hot flashes often stem from changes in the body’s temperature control system, primarily due to decreased estrogen levels. This hormonal shift leads to increased activity of certain brain chemicals, specifically norepinephrine, and decreased levels of serotonin.
Our hypothesis was that folic acid might help ease these symptoms by interacting with the same brain chemicals that estrogen does. Over the years, research has shown that folic acid can produce an antidepressant-like effect, affecting both noradrenergic and serotonergic receptors in the brain. This raises the intriguing possibility that it could offer a similar benefit when it comes to managing hot flashes, although the specific effectiveness of folate on this issue is still under investigation.
While preliminary data supports our ideas, more research is needed to draw firm conclusions. It’s exciting to consider the potential of folic acid as a natural remedy for hot flashes, but we must proceed with caution until further evidence is available.
Our hypothesis was that folic acid might help ease these symptoms by interacting with the same brain chemicals that estrogen does. Over the years, research has shown that folic acid can produce an antidepressant-like effect, affecting both noradrenergic and serotonergic receptors in the brain. This raises the intriguing possibility that it could offer a similar benefit when it comes to managing hot flashes, although the specific effectiveness of folate on this issue is still under investigation.
While preliminary data supports our ideas, more research is needed to draw firm conclusions. It’s exciting to consider the potential of folic acid as a natural remedy for hot flashes, but we must proceed with caution until further evidence is available.
4
We investigated the effects of folate in a study that included 51 postmenopausal women experiencing significant hot flashes. These women were carefully divided into groups: some received L-methionine, while others received a placebo, all while taking folate and methylcobalamin. The aim was to determine if folate could help alleviate the discomfort of hot flashes.
Despite the thoughtful setup and monitoring of participants, the results revealed no significant benefit of L-methionine for reducing hot flashes in comparison to the placebo group. We noted that both groups showed a decrease in hot flash frequency, but not enough to claim that folate had any positive effect.
It is important to highlight that folate was administered alongside L-methionine, making it challenging to isolate its potential impact on hot flashes. Consequently, while we explored its role, the findings suggest that folate alone might not play a significant part in managing this symptom for postmenopausal women.
Despite the thoughtful setup and monitoring of participants, the results revealed no significant benefit of L-methionine for reducing hot flashes in comparison to the placebo group. We noted that both groups showed a decrease in hot flash frequency, but not enough to claim that folate had any positive effect.
It is important to highlight that folate was administered alongside L-methionine, making it challenging to isolate its potential impact on hot flashes. Consequently, while we explored its role, the findings suggest that folate alone might not play a significant part in managing this symptom for postmenopausal women.
3
We conducted a double-blind, placebo-controlled trial involving 164 postmenopausal women suffering from frequent hot flashes. Over 12 weeks, half received a daily 5 mg folic acid supplement, while the other half received a placebo.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eases hot flashes
2 people found this helpful
Really works. It is very helpful for easing hot flashes of menopause and assists thyroid function. I previously used it for period pain, taking two pills at the onset, and within ten minutes the pain would diminish. If I didn't achieve complete relief, I would repeat the dose and, like magic, no more cramps. It also boosts energy for those with ME/CFS or constant tiredness. I appreciate that it contains B12 as well. A definite thumbs up from me. :)
9
Eases hot flashes
Indispensable during menopause. I have early menopause, and my gynecologist recommended folic acid, magnesium, calcium, and vitamin D. Headaches have ceased, sleep is normal, and mood swings have smoothed. My hot flashes occur much less often now. I am satisfied with this manufacturer's folic acid. I hope my review is helpful.
9
Eases hot flashes
This gives me energy and alleviates hot flashes at the beginning of menopause and PMS. My nervous system feels calmer, and I am less irritable. I can see the results, which makes me pleased.
7.5
Eases hot flashes
I take folic acid according to my age. This drug is necessary for women, and I have no complaints about the quality. It nourishes the nervous system, improves metabolism, and while the taste is unimportant to me, niacin provides energy. Hot flashes have become far less tormenting.
9
Reduces hot flashes
1 people found this helpful
This is for my wife. It has reduced her heart palpitations and hot flashes significantly. Moreover, her irritability has decreased greatly. It is a high-quality product, and she did not report any issues with the taste.
Frequently Asked Questions
9
Reduces hot flashes
An essential vitamin after 40, it improves skin, nails, and hair, rejuvenates the body, and delays menopause. After ten days of use, my hot flashes were much reduced.
9
Reduces hot flashes
1 people found this helpful
This is for my wife. It has reduced her heart palpitations and hot flashes significantly. Moreover, her irritability has decreased greatly. It is a high-quality product, and she did not report any issues with the taste.
7.5
Eases hot flashes
Folic acid is crucial after 40. It postpones menopause and significantly alleviates symptoms, such as hot flashes, irritability, and depression. Timely intake helps maintain memory and cognitive speed, serving as a good prevention of Alzheimer's. Careful monitoring is essential when taking the drug.
9
Eases hot flashes
Indispensable during menopause. I have early menopause, and my gynecologist recommended folic acid, magnesium, calcium, and vitamin D. Headaches have ceased, sleep is normal, and mood swings have smoothed. My hot flashes occur much less often now. I am satisfied with this manufacturer's folic acid. I hope my review is helpful.
9
Eases hot flashes
This gives me energy and alleviates hot flashes at the beginning of menopause and PMS. My nervous system feels calmer, and I am less irritable. I can see the results, which makes me pleased.
3
We conducted a double-blind, placebo-controlled trial involving 164 postmenopausal women suffering from frequent hot flashes. Over 12 weeks, half received a daily 5 mg folic acid supplement, while the other half received a placebo.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
9
We conducted a study with 70 menopausal women, randomly assigning them to receive either folic acid or a placebo for four weeks. Through questionnaires and hot flash diaries, we monitored changes in the severity, duration, and frequency of hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
8
We investigated the effects of folic acid on hot flashes in postmenopausal women. In our study, 46 women were divided into two groups: one received daily folic acid supplements, while the other received a placebo for four weeks.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
References
- Ewies A, Ahmed I, Al-Azzawi F, Pitkin J, Gupta P, et al. Folic acid supplementation in postmenopausal women with hot flushes: phase III randomised double-blind placebo-controlled trial. BJOG. 2021;128:2024. doi:10.1111/1471-0528.16739
- Bani S, Hasanpour S, Farzad Rik L, Hasankhani H, Sharami SH. The effect of folic Acid on menopausal hot flashes: a randomized clinical trial. J Caring Sci. 2013;2:131. doi:10.5681/jcs.2013.016
- Gaweesh SS, Abdel-Gawad MM, Nagaty AM, Ewies AA. Folic acid supplementation may cure hot flushes in postmenopausal women: a prospective cohort study. Gynecol Endocrinol. 2010;26:658. doi:10.3109/09513591003686288
- Gaweesh S, Ewies AA. Folic acid supplementation cures hot flushes in postmenopausal women. Med Hypotheses. 2010;74:286. doi:10.1016/j.mehy.2009.09.010
- Guttuso T, McDermott MP, Ng P, Kieburtz K. Effect of L-methionine on hot flashes in postmenopausal women: a randomized controlled trial. Menopause. 2009;16:1004. doi:10.1097/gme.0b013e3181a2fa76
